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Details on Person EML4(1-486)-p-7Y-ALK(1058-1620) fusion [cytosol]

Class:Id	EntityWithAccessionedSequence:9699918
_displayName	EML4(1-486)-p-7Y-ALK(1058-1620) fusion [cytosol]
_timestamp	2023-03-30 18:46:35
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9699845] Rothfels, Karen, 2020-09-14
disease	[Disease:1247848] non-small cell lung carcinoma
endCoordinate	486
hasModifiedResidue	[FragmentInsertionModification:9832407] Insertion of residues 1058 to 1620 at 487 from UniProt:Q9UM73 ALK [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699796] O4'-phospho-L-tyrosine at 1096 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
literatureReference	[LiteratureReference:9648139] Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
modified	[InstanceEdit:9832399] Orlic-Milacic, Marija, 2023-03-30 [InstanceEdit:9832410] Orlic-Milacic, Marija, 2023-03-30
name	EML4(1-486)-p-7Y-ALK(1058-1620) fusion Echinoderm microtubule-associated protein-like 4 EMAL4_HUMAN
referenceEntity	[ReferenceGeneProduct:69902] UniProt:Q9HC35 EML4 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9699950] R-HSA-9699918.2
startCoordinate	1
(hasComponent)	[Complex:9700010] EML4(1-486)-p-7Y ALK(1058-1620) fusion dimer [cytosol] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9905819] Update Tracker - [EntityWithAccessionedSequence:9699918] EML4(1-486)-p-7Y-ALK(1058-1620) fusion [cytosol] - v85:[add_removeHasModifiedResidue, modifyName]
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No pathways have been reviewed or authored by EML4(1-486)-p-7Y-ALK(1058-1620) fusion [cytosol] (9699918)