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Query author contributions in Reactome

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Details on Person EML4(1-223)-ALK(1059-1620) fusion [cytosol]

Class:IdEntityWithAccessionedSequence:9699862
_displayNameEML4(1-223)-ALK(1059-1620) fusion [cytosol]
_timestamp2021-02-17 00:35:17
compartment[Compartment:70101] cytosol
created[InstanceEdit:9699845] Rothfels, Karen, 2020-09-14
crossReference[DatabaseIdentifier:9713348] COSMIC:COSF411
disease[Disease:1247848] non-small cell lung carcinoma
endCoordinate223
hasModifiedResidue[FragmentInsertionModification:9699856] Insertion of residues 1059 to 1620 at 224 from UniProt:Q9UM73 ALK
literatureReference[LiteratureReference:9699710] Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer
[LiteratureReference:9701376] Role of ERK-BIM and STAT3-survivin signaling pathways in ALK inhibitor-induced apoptosis in EML4-ALK-positive lung cancer
modified[InstanceEdit:9701414] Rothfels, Karen, 2020-09-26
[InstanceEdit:9713435] Rothfels, Karen, 2021-01-26
[InstanceEdit:9715307] Rothfels, Karen, 2021-02-17
nameEML4(1-223)-ALK(1059-1620) fusion
Echinoderm microtubule-associated protein-like 4
EMAL4_HUMAN
variant 3a
EXON6-EXON20
referenceEntity[ReferenceGeneProduct:69902] UniProt:Q9HC35 EML4 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9699964] R-HSA-9699862.1
startCoordinate1
(hasComponent)[Complex:9699985] EML4(1-223)-ALK(1059-1620) fusion dimer [cytosol] [Homo sapiens]
(hasMember)[CandidateSet:9700080] ALK fusion proteins [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by EML4(1-223)-ALK(1059-1620) fusion [cytosol] (9699862)
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