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Details on Person anaplastic large cell lymphoma

Class:IdDisease:9699595
_displayNameanaplastic large cell lymphoma
_timestamp2020-09-14 12:32:26
created[InstanceEdit:9699596] Rothfels, Karen, 2020-09-14
definitionA non-Hodgkin lymphoma involving aberrant T-cells.
identifier0050744
nameanaplastic large cell lymphoma
referenceDatabase[ReferenceDatabase:1247631] DOID
(disease)[BlackBoxEvent:9725338] NPM1-ALK-dependent BCL2A1 gene expression [Homo sapiens]
[BlackBoxEvent:9725357] NPM1-ALK-dependent CEBPB gene expression [Homo sapiens]
[BlackBoxEvent:9850958] pY-STAT3 dimer translocates to the nucleus downstream of ALK mutants [Homo sapiens]
[BlackBoxEvent:9851068] Crizotinib-driven IL10RA gene expression in NPM1-ALK [Homo sapiens]
[Reaction:9851076] p-T,Y MAPK8,9 bind TP53 [Homo sapiens]
[BlackBoxEvent:9851077] JNK-dependent inhibition of TP53 ubiquitination [Homo sapiens]
[BlackBoxEvent:9851078] NPM1-ALK-dependent MAPK8,9 phosphorylation [Homo sapiens]
[BlackBoxEvent:9851079] p-T,Y MAPK8,9 translocate to the nucleus [Homo sapiens]
[Reaction:9851084] JUNB dimer binds GZMB promoter [Homo sapiens]
[BlackBoxEvent:9851088] JUNB- and NPM1-ALK-mediated GZMB gene expression [Homo sapiens]
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No pathways have been reviewed or authored by anaplastic large cell lymphoma (9699595)