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Details on Person The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib
| Class:Id | LiteratureReference:9699384 |
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| _displayName | The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib |
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| _timestamp | 2020-09-14 12:20:02 |
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| author | [Person:9699379] Albers, C
[Person:9699376] Leischner, H
[Person:9699378] Verbeek, M
[Person:9655588] Yu, C
[Person:9699383] Illert, A L
[Person:9699380] Peschel, C
[Person:9699382] von Bubnoff, N
[Person:9699377] Duyster, J |
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| created | [InstanceEdit:9699381] Rothfels, Karen, 2020-09-14 |
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| journal | Leukemia |
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| pages | 1416-8 |
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| pubMedIdentifier | 23392356 |
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| title | The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib |
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| volume | 27 |
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| year | 2013 |
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| (literatureReference) | [Reaction:9702508] FLT mutants bind type I TKIs [Homo sapiens]
[Reaction:9702510] FLT mutants bind type II TKIs [Homo sapiens]
[FailedReaction:9702601] midostaurin-resistant FLT3 mutants don't bind midostaurin [Homo sapiens]
[FailedReaction:9702618] quizartinib-resistant FLT3 mutants don't bind quizartinib [Homo sapiens]
[FailedReaction:9702629] sunitinib-resistant FLT3 mutants don't bind sunitinib [Homo sapiens]
[DefinedSet:9699522] sorafenib-sensitive FLT3 mutants [plasma membrane] [Homo sapiens]
[DefinedSet:9699525] quizartinib-resistant FLT3 mutants [plasma membrane] [Homo sapiens]
[DefinedSet:9699529] midostaurin-sensitive FLT3 mutants [plasma membrane] [Homo sapiens]
[DefinedSet:9699530] sorafenib-resistant FLT3 mutants [plasma membrane] [Homo sapiens]
[DefinedSet:9699532] sunitinib-sensitive FLT3 mutants [plasma membrane] [Homo sapiens] |
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