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Details on Person A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells

Class:IdLiteratureReference:9698993
_displayNameA Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells
_timestamp2020-09-05 04:40:06
author[Person:9681520] Hoffmann, Markus
[Person:9681523] Kleine-Weber, Hannah
[Person:5607324] Pöhlmann, Stefan
created[InstanceEdit:9699008] Gillespie, Marc E, 2020-09-05
journalMol. Cell
pages779-784.e5
pubMedIdentifier32362314
titleA Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells
volume78
year2020
(literatureReference)[BlackBoxEvent:9698988] Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid [Homo sapiens]
[Reaction:9699007] FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis [Homo sapiens]
[Pathway:9733458] Induction of Cell-Cell Fusion [Homo sapiens]
[Reaction:9769949] FURIN Mediated SARS-CoV-2 Spike Protein Cleavage [Homo sapiens]
[Summation:9698991] SARS-CoV-2 virions attached to the host cell surface via a c...
[Summation:9699005] In a SARS-CoV-2 infection the cellular protease furin cleave...
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