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Details on Person NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells

Class:IdLiteratureReference:9698776
_displayNameNOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells
_timestamp2020-08-28 15:28:03
author[Person:9698781] Jayavelu, A K
[Person:9698745] Müller, J P
[Person:9698749] Bauer, R
[Person:9698766] Böhmer, S-A
[Person:9698756] Lässig, J
[Person:9698746] Cerny-Reiterer, S
[Person:9698763] Sperr, W R
[Person:9698764] Valent, P
[Person:9698779] Maurer, B
[Person:6786099] Moriggl, R
[Person:9698767] Schröder, K
[Person:9698769] Shah, A M
[Person:5321873] Fischer, M
[Person:9698742] Scholl, S
[Person:9698780] Barth, J
[Person:9698768] Oellerich, T
[Person:2453643] Berg, T
[Person:9649416] Serve, H
[Person:9698734] Frey, S
[Person:9027413] Fischer, T
[Person:9027377] Heidel, F H
[Person:9698752] Böhmer, F-D
created[InstanceEdit:9698733] Rothfels, Karen, 2020-08-28
journalLeukemia
modified[InstanceEdit:9698790] Rothfels, Karen, 2020-08-28
pages473-83
pubMedIdentifier26308771
titleNOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells
volume30
year2016
(literatureReference)[Reaction:9698408] PTPRJ dephosphorylates active FLT3 [Homo sapiens]
[Reaction:9698754] p-STAT5 binds the NOX4 promoter [Homo sapiens]
[Reaction:9698758] FLT3 ITD- and NOX4-dependent H2O2 production [Homo sapiens]
[BlackBoxEvent:9698762] FLT3 ITD- and STAT5-dependent NOX4 gene expression [Homo sapiens]
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