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Details on Person Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ
| Class:Id | LiteratureReference:9698765 |
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| _displayName | Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ |
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| _timestamp | 2020-08-28 15:28:39 |
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| author | [Person:9697869] Godfrey, Rinesh
[Person:9697862] Arora, Deepika
[Person:9697868] Bauer, Reinhard
[Person:9697863] Stopp, Sabine
[Person:9697864] Müller, Jörg P
[Person:9698730] Heinrich, Theresa
[Person:9697865] Böhmer, Sylvia-Annette
[Person:2870257] Dagnell, Markus
[Person:9698777] Schnetzke, Ulf
[Person:9698755] Scholl, Sebastian
[Person:9698771] Östman, Arne
[Person:9697797] Böhmer, Frank-D |
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| created | [InstanceEdit:9698733] Rothfels, Karen, 2020-08-28 |
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| journal | Blood |
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| modified | [InstanceEdit:9698791] Rothfels, Karen, 2020-08-28 |
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| pages | 4499-511 |
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| pubMedIdentifier | 22438257 |
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| title | Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ |
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| volume | 119 |
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| year | 2012 |
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| (literatureReference) | [Reaction:9698408] PTPRJ dephosphorylates active FLT3 [Homo sapiens]
[Reaction:9698754] p-STAT5 binds the NOX4 promoter [Homo sapiens]
[Reaction:9698758] FLT3 ITD- and NOX4-dependent H2O2 production [Homo sapiens]
[BlackBoxEvent:9698762] FLT3 ITD- and STAT5-dependent NOX4 gene expression [Homo sapiens]
[Pathway:9702518] STAT5 activation downstream of FLT3 ITD mutants [Homo sapiens] |
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No pathways have been reviewed or authored by Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ (9698765)
