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Details on Person Rothfels, Karen, 2020-08-24

Class:IdInstanceEdit:9698204
_displayNameRothfels, Karen, 2020-08-24
_timestamp2020-08-24 14:21:54
author[Person:1226097] Rothfels, Karen
dateTime2020-08-24 14:21:51
(modified)[Pathway:9607240] FLT3 Signaling [Homo sapiens]
[Reaction:9607304] SOS1-mediated nucleotide exchange of RAS downstream of FLT3 [Homo sapiens]
[PathwayDiagram:9645667] Diagram of FLT3 Signaling, Signaling by FLT3 ITD and TKD mutants, FLT3 mutants bind TKIs, KW2449-resistant FLT3 mutants, crenolanib-resistant FLT3 mutants, gilteritinib-resistant FLT3 mutants, lestaurtinib-resistant FLT3 mutants, linifanib-resistant FLT3 mutants, midostaurin-resistant FLT3 mutants, pexidartinib-resistant FLT3 mutants, ponatinib-resistant FLT3 mutants, quizartinib-resistant FLT3 mutants, semaxanib-resistant FLT3 mutants, sorafenib-resistant FLT3 mutants, sunitinib-resistant FLT3 mutants, tamatinib-resistant FLT3 mutants, tandutinib-resistant FLT3 mutants, Signaling by FLT3 fusion proteins, and FLT3 signaling by CBL mutants
[Reaction:9695841] FLT3 mutant dimers bind GRB2 [Homo sapiens]
[Reaction:9695845] FLT3 mutant dimers:GRB2 bind SOS1 [Homo sapiens]
[Reaction:9698000] FLT3 mutants:GRB2 bind GAB2 [Homo sapiens]
[Reaction:9698003] FLT3 mutants phosphorylate GAB2 [Homo sapiens]
[Reaction:9698005] FLT3 ITD mutants phosphorylate STAT5 [Homo sapiens]
[Reaction:9698007] FLT3 ITD mutants bind STAT5 through GAB2:PTPN11 [Homo sapiens]
[Reaction:9698008] FLT3 mutants:GRB2:p-Y-GAB2 binds PTPN11 [Homo sapiens]
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No pathways have been reviewed or authored by Rothfels, Karen, 2020-08-24 (9698204)
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