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Details on Person FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications

Class:Id	LiteratureReference:9697839
_displayName	FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications
_timestamp	2020-08-21 13:59:39
author	[Person:9605262] Kazi, Julhash U [Person:9606963] R�nnstrand, Lars
created	[InstanceEdit:9697840] Rothfels, Karen, 2020-08-21
journal	Physiol. Rev.
pages	1433-1466
pubMedIdentifier	31066629
title	FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications
volume	99
year	2019
(literatureReference)	[Pathway:9682385] FLT3 signaling in disease [Homo sapiens] [Reaction:9695841] FLT3 mutant dimers bind GRB2 [Homo sapiens] [Reaction:9695845] FLT3 mutant dimers:GRB2 bind SOS1 [Homo sapiens] [Reaction:9695853] FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS [Homo sapiens] [Reaction:9698000] FLT3 mutants:GRB2 bind GAB2 [Homo sapiens] [Reaction:9698003] FLT3 mutants phosphorylate GAB2 [Homo sapiens] [Reaction:9698005] FLT3 ITD mutants phosphorylate STAT5 [Homo sapiens] [Reaction:9698007] FLT3 ITD mutants bind STAT5 through GAB2:PTPN11 [Homo sapiens] [Reaction:9698008] FLT3 mutants:GRB2:p-Y-GAB2 binds PTPN11 [Homo sapiens] [BlackBoxEvent:9698033] p-STAT5 translocates to nucleus downstream of mutant FLT3 [Homo sapiens] List all 44 refering instances
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No pathways have been reviewed or authored by FMS-like Tyrosine Kinase 3/FLT3: From Basic Science to Clinical Implications (9697839)