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Details on Person Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex

Class:IdLiteratureReference:9697033
_displayNameStructural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex
_timestamp2020-11-19 16:23:09
author[Person:8942083] Chen, James
[Person:9697037] Malone, Brandon
[Person:9697038] Llewellyn, Eliza
[Person:9697029] Grasso, Michael
[Person:9697030] Shelton, Patrick M M
[Person:9697031] Olinares, Paul Dominic B
[Person:9697036] Maruthi, Kashyap
[Person:9696893] Eng, Edward T
[Person:9697035] Vatandaslar, Hasan
[Person:3772103] Chait, Brian T
[Person:5609861] Kapoor, Tarun M
[Person:114051] Darst, SA
[Person:9697032] Campbell, Elizabeth A
created[InstanceEdit:9697039] Orlic-Milacic, Marija, 2020-08-04
journalCell
modified[InstanceEdit:9707748] Orlic-Milacic, Marija, 2020-11-19
pages1560-1573.e13
pubMedIdentifier32783916
titleStructural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex
volume182
year2020
(literatureReference)[BlackBoxEvent:9694265] nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template [Homo sapiens]
[Pathway:9694271] Assembly of the SARS-CoV-2 Replication-Transcription Complex (RTC) [Homo sapiens]
[Reaction:9694524] nsp13 binds nsp12 [Homo sapiens]
[Pathway:9694682] SARS-CoV-2 Genome Replication and Transcription [Homo sapiens]
[Pathway:9694686] Replication of the SARS-CoV-2 genome [Homo sapiens]
[Pathway:9694786] Transcription of SARS-CoV-2 sgRNAs [Homo sapiens]
[Summation:9694391] nsp13, which functions as the viral helicase, is as a part o...
[Summation:9694670] nsp13 of SARS-CoV-2 possesses the nucleoside triphosphate hy...
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