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Details on Person E protein gets N-glycosylated

Class:Id	BlackBoxEvent:9694790
_displayName	E protein gets N-glycosylated
_doRelease	TRUE
_timestamp	2022-04-29 20:03:37
authored	[InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:9694660] Cook, Justin, 2020-07-07
disease	[Disease:9683912] COVID-19
edited	[InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
inferredFrom	[BlackBoxEvent:9683669] E protein gets N-glycosylated [Homo sapiens]
input	[OtherEntity:9683033] nucleotide-sugar [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:9694312] nascent E [endoplasmic reticulum lumen] [Severe acute respiratory syndrome coronavirus 2]
isChimeric	FALSE
literatureReference	[LiteratureReference:9683094] Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein
modified	[InstanceEdit:9697028] Gillespie, Marc E, 2020-08-04 [InstanceEdit:9698635] Cook, Justin, 2020-08-27 [InstanceEdit:9698837] Stephan, Ralf, 2020-08-30 [InstanceEdit:9699043] Gillespie, Marc E, 2020-09-09 [InstanceEdit:9773094] Gillespie, Marc E, 2022-04-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	E protein gets N-glycosylated
output	[OtherEntity:9683046] nucleoside 5'-diphosphate(3−) [endoplasmic reticulum lumen] [SimpleEntity:156540] H+ [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:9694754] N-glycan E [endoplasmic reticulum lumen] [Severe acute respiratory syndrome coronavirus 2]
precedingEvent	[BlackBoxEvent:9694280] mRNA4 is translated to protein E [Homo sapiens] [BlackBoxEvent:9694733] Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) [Homo sapiens]
relatedSpecies	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
releaseDate	2020-09-15
reviewed	[InstanceEdit:9699044] Acencio, Marcio Luis, 2020-09-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9694890] R-HSA-9694790.3
summation	[Summation:9694403] This COVID-19 event has been created by a combination of computational inference (see https://reactome.org/documentation/inferred-events) from SARS-CoV-1 data and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway. A minor proportion of the E protein is modified by N-linked glycosylation. This variant appears to be more likely to form multimers, and it shows a different membrane topology than the main variant (Yuan et al, 2006).
(hasEvent)	[Pathway:9694493] Maturation of protein E [Homo sapiens]
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No pathways have been reviewed or authored by E protein gets N-glycosylated (9694790)