Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person This COVID-19 pathway has been created by a combination of c...

Class:IdSummation:9694747
_displayNameThis COVID-19 pathway has been created by a combination of c...
_timestamp2020-08-30 02:11:34
created[InstanceEdit:9694660] Cook, Justin, 2020-07-07
literatureReference[LiteratureReference:9682922] Expression of SARS-coronavirus envelope protein in Escherichia coli cells alters membrane permeability
[LiteratureReference:9682946] Biochemical and functional characterization of the membrane association and membrane permeabilizing activity of the severe acute respiratory syndrome coronavirus envelope protein
[LiteratureReference:9683075] The envelope protein of severe acute respiratory syndrome coronavirus interacts with the non-structural protein 3 and is ubiquitinated
modified[InstanceEdit:9697788] D'Eustachio, Peter, 2020-08-20
[InstanceEdit:9698837] Stephan, Ralf, 2020-08-30
textThis COVID-19 pathway has been created by a combination of computational inference from SARS-CoV-1 data (https://reactome.org/documentation/inferred-events) and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway.

The envelope protein (E) gets palmitoylated and ubiquitinated after translation. It forms trimers that show porin activity but does not localize to the cell membrane (Tan et al, 2004; Liao et al, 2006; Alvarez et al, 2011)
(summation)[Pathway:9694493] Maturation of protein E [Homo sapiens]
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No pathways have been reviewed or authored by This COVID-19 pathway has been created by a combination of c... (9694747)