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Details on Person N dimer [cytosol]

Class:Id	Complex:9694702
_displayName	N dimer [cytosol]
_timestamp	2022-01-25 09:26:06
authored	[InstanceEdit:9696945] Stephan, Ralf, 2020-07-30
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9694660] Cook, Justin, 2020-07-07
disease	[Disease:9683912] COVID-19
hasComponent	[EntityWithAccessionedSequence:9729340] SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] [Severe acute respiratory syndrome coronavirus 2] [EntityWithAccessionedSequence:9729340] SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] [Severe acute respiratory syndrome coronavirus 2]
isChimeric	FALSE
literatureReference	[LiteratureReference:9697000] Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein [LiteratureReference:9762462] Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain [LiteratureReference:9731265] Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids
modified	[InstanceEdit:9696709] Orlic-Milacic, Marija, 2020-07-28 [InstanceEdit:9697017] Stephan, Ralf, 2020-08-04 [InstanceEdit:9728571] Stephan, Ralf, 2021-04-21 [InstanceEdit:9730653] Stephan, Ralf, 2021-05-10 [InstanceEdit:9762464] Stephan, Ralf, 2022-01-25
name	N dimer
species	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
stableIdentifier	[StableIdentifier:9694815] R-COV-9694702.3
(activeUnit)	[PositiveRegulation:9765919] Positive regulation by 'N:CHUK:IKBKB:IKBKG [cytosol]' [PositiveRegulation:9765922] Positive regulation by 'N:TAK1complex [cytosol]' [NegativeRegulation:9765923] Negative regulation by 'TRIM25:N [cytosol]' [NegativeRegulation:9765939] Negative regulation by 'STAT1,STAT2:N [cytosol]'
(hasComponent)	[Complex:9694461] encapsidated SARS-CoV-2 genomic RNA (plus strand) [cytosol] [Severe acute respiratory syndrome coronavirus 2] [Complex:9717677] DDX58:N [cytosol] [Homo sapiens] [Complex:9729443] STAT1,STAT2:N [cytosol] [Homo sapiens] [Complex:9729447] TRIM25:N [cytosol] [Homo sapiens] [Complex:9729509] 14-3-3 dimer:N [cytosol] [Homo sapiens] [Complex:9729513] G3BP1,G3BP2:N [cytosol] [Homo sapiens] [Complex:9755729] N:MAVS [cytosol] [Homo sapiens] [Complex:9755745] N:TAK1complex [cytosol] [Homo sapiens] [Complex:9755778] N:M:PDPK1 [plasma membrane] [Homo sapiens] [Complex:9755930] N:CHUK:IKBKB:IKBKG [cytosol] [Homo sapiens] List all 12 refering instances
(input)	[BlackBoxEvent:9694345] Nucleoprotein translocates to the nucleolus [Homo sapiens] [BlackBoxEvent:9694568] Nucleoprotein translocates to the ERGIC outer membrane [Homo sapiens] [BlackBoxEvent:9694575] Nucleoprotein translocates to the plasma membrane [Homo sapiens] [Reaction:9717658] SARS-CoV-2 N binds DDX58 [Homo sapiens] [Reaction:9729437] SARS-CoV-2 N binds to TRIM25 [Homo sapiens] [Reaction:9729454] SARS-CoV-2 N protein binds STAT1, STAT2 [Homo sapiens] [Reaction:9729481] SARS-CoV-2 N binds to G3BP1,G3BP2 [Homo sapiens] [Reaction:9729500] SARS-CoV-2 N binds to 14-3-3 proteins [Homo sapiens] [Reaction:9755734] SARS-CoV-2 N binds IKBKB [Homo sapiens] [Reaction:9755747] SARS-CoV-2 N binds MAVS [Homo sapiens] List all 15 refering instances
(output)	[Reaction:9694363] Dimerisation of nucleoprotein [Homo sapiens] [Reaction:9694723] Uncoating of SARS-CoV-2 Genome [Homo sapiens]
(regulator)	[PositiveRegulation:9694608] Positive regulation by 'N dimer [cytosol]'
(updatedInstance)	[_UpdateTracker:9902302] Update Tracker - [Complex:9694702] N dimer [cytosol] - v77:[add_removeHasComponent, modifyName] [_UpdateTracker:9903933] Update Tracker - [Complex:9694702] N dimer [cytosol] - v80:[addLiteratureReference, modifyName]
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No pathways have been reviewed or authored by N dimer [cytosol] (9694702)