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Details on Person Ubiquination of protein E

Class:Id	BlackBoxEvent:9694529
_displayName	Ubiquination of protein E
_doRelease	TRUE
_timestamp	2022-04-29 20:05:09
authored	[InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9694660] Cook, Justin, 2020-07-07
disease	[Disease:9683912] COVID-19
edited	[InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
inferredFrom	[BlackBoxEvent:9683679] Ubiquination of protein E [Homo sapiens]
input	[EntityWithAccessionedSequence:9694305] 3xPalmC-E [endoplasmic reticulum lumen] [Severe acute respiratory syndrome coronavirus 2] [DefinedSet:8943136] Ub [endoplasmic reticulum membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9683075] The envelope protein of severe acute respiratory syndrome coronavirus interacts with the non-structural protein 3 and is ubiquitinated
modified	[InstanceEdit:9697028] Gillespie, Marc E, 2020-08-04 [InstanceEdit:9698635] Cook, Justin, 2020-08-27 [InstanceEdit:9698837] Stephan, Ralf, 2020-08-30 [InstanceEdit:9699043] Gillespie, Marc E, 2020-09-09 [InstanceEdit:9773094] Gillespie, Marc E, 2022-04-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Ubiquination of protein E
output	[EntityWithAccessionedSequence:9694423] Ub-3xPalmC-E [endoplasmic reticulum lumen] [Severe acute respiratory syndrome coronavirus 2]
precedingEvent	[Reaction:9694401] E protein gets palmitoylated [Homo sapiens] [BlackBoxEvent:9694280] mRNA4 is translated to protein E [Homo sapiens]
relatedSpecies	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
releaseDate	2020-09-15
reviewed	[InstanceEdit:9699044] Acencio, Marcio Luis, 2020-09-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9695076] R-HSA-9694529.3
summation	[Summation:9694604] This COVID-19 event has been created by a combination of computational inference (see https://reactome.org/documentation/inferred-events) from SARS-CoV-1 data and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway. Viral E protein is ubiquitinated both in vitro and in cells (Alvarez et al, 2011).
(hasEvent)	[Pathway:9694493] Maturation of protein E [Homo sapiens]
(precedingEvent)	[Reaction:9694452] Protein E forms a homopentamer [Homo sapiens]
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No pathways have been reviewed or authored by Ubiquination of protein E (9694529)