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Details on Person 3CLp dimer:3CLp inhibitors [cytosol]

Class:Id	Complex:9694375
_displayName	3CLp dimer:3CLp inhibitors [cytosol]
_timestamp	2022-01-27 08:57:08
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9694660] Cook, Justin, 2020-07-07
disease	[Disease:9683912] COVID-19
hasComponent	[Complex:9694407] 3CLp dimer [cytosol] [Severe acute respiratory syndrome coronavirus 2] [DefinedSet:9694748] nsp5 [cytosol] [Severe acute respiratory syndrome coronavirus 2] [DefinedSet:9694748] nsp5 [cytosol] [Severe acute respiratory syndrome coronavirus 2] [DefinedSet:9731705] 3CLp inhibitors [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9731715] Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease [LiteratureReference:9731677] Structure of M^pro from SARS-CoV-2 and discovery of its inhibitors [LiteratureReference:9762564] Considerations for the discovery and development of 3-chymotrypsin-like cysteine protease inhibitors targeting SARS-CoV-2 infection
modified	[InstanceEdit:9696709] Orlic-Milacic, Marija, 2020-07-28 [InstanceEdit:9731693] Stephan, Ralf, 2021-05-24 [InstanceEdit:9762563] Stephan, Ralf, 2022-01-27
name	3CLp dimer:3CLp inhibitors
species	[Species:9681683] Severe acute respiratory syndrome coronavirus 2
stableIdentifier	[StableIdentifier:9694865] R-COV-9694375.3
(output)	[BlackBoxEvent:9694592] 3CLp dimer binds 3CLp inhibitors [Homo sapiens]
(regulator)	[NegativeRegulation:9694290] Negative regulation by '3CLp dimer:3CLp inhibitors [cytosol]'
(updatedInstance)	[_UpdateTracker:9902281] Update Tracker - [Complex:9694375] 3CLp dimer:3CLp inhibitors [cytosol] - v77:[updateContainedComponent] [_UpdateTracker:9902712] Update Tracker - [Complex:9694375] 3CLp dimer:3CLp inhibitors [cytosol] - v78:[addLiteratureReference, add_removeHasComponent, modifyName, removeSummation] [_UpdateTracker:9903045] Update Tracker - [Complex:9694375] 3CLp dimer:3CLp inhibitors [cytosol] - v80:[add_removeLiteratureReference]
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No pathways have been reviewed or authored by 3CLp dimer:3CLp inhibitors [cytosol] (9694375)