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Details on Person Dimerisation of nucleoprotein
Class:Id Reaction:9694363
_displayName Dimerisation of nucleoprotein
_doRelease TRUE
_timestamp 2022-04-29 20:03:34
authored [InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
compartment [Compartment:70101] cytosol
created [InstanceEdit:9694660] Cook, Justin, 2020-07-07
disease [Disease:9683912] COVID-19
edited [InstanceEdit:9698836] Stephan, Ralf, 2020-08-28
input [EntityWithAccessionedSequence:9729340] SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] [Severe acute respiratory syndrome coronavirus 2] [EntityWithAccessionedSequence:9729340] SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] [Severe acute respiratory syndrome coronavirus 2]
isChimeric FALSE
literatureReference [LiteratureReference:9697000] Architecture and self-assembly of the SARS-CoV-2 nucleocapsid protein [LiteratureReference:9713210] Phosphorylation modulates liquid-liquid phase separation of the SARS-CoV-2 N protein [LiteratureReference:9731265] Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids [LiteratureReference:9731272] Multivalent binding of the partially disordered SARS-CoV-2 nucleocapsid phosphoprotein dimer to RNA [LiteratureReference:9762462] Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain [LiteratureReference:9762482] Targeted in situ cross-linking mass spectrometry and integrative modeling reveal the architectures of three proteins from SARS-CoV-2
modified [InstanceEdit:9697017] Stephan, Ralf, 2020-08-04 [InstanceEdit:9697028] Gillespie, Marc E, 2020-08-04 [InstanceEdit:9698635] Cook, Justin, 2020-08-27 [InstanceEdit:9698837] Stephan, Ralf, 2020-08-30 [InstanceEdit:9699043] Gillespie, Marc E, 2020-09-09 [InstanceEdit:9713198] Stephan, Ralf, 2021-01-22 [InstanceEdit:9730597] Stephan, Ralf, 2021-05-10 [InstanceEdit:9730600] Stephan, Ralf, 2021-05-10 [InstanceEdit:9731286] Stephan, Ralf, 2021-05-19 [InstanceEdit:9758621] Stephan, Ralf, 2021-11-19 [InstanceEdit:9762464] Stephan, Ralf, 2022-01-25 [InstanceEdit:9766714] Stephan, Ralf, 2022-02-24 [InstanceEdit:9773094] Gillespie, Marc E, 2022-04-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Dimerisation of nucleoprotein
output [Complex:9694702] N dimer [cytosol] [Severe acute respiratory syndrome coronavirus 2]
precedingEvent
relatedSpecies [Species:9681683] Severe acute respiratory syndrome coronavirus 2
releaseDate 2020-09-15
reviewed [InstanceEdit:9699044] Acencio, Marcio Luis, 2020-09-09
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9694875] R-HSA-9694363.6
summation [Summation:9694671] Nucleoprotein of SARS-Cov-2 forms stable dimers in solution ...
(hasEvent) [Pathway:9694631] Maturation of nucleoprotein [Homo sapiens]
(precedingEvent) [BlackBoxEvent:9694344] Synthesis of SARS-CoV-2 minus strand subgenomic mRNAs by template switching [Homo sapiens] [BlackBoxEvent:9694345] Nucleoprotein translocates to the nucleolus [Homo sapiens] [BlackBoxEvent:9694568] Nucleoprotein translocates to the ERGIC outer membrane [Homo sapiens] [BlackBoxEvent:9694575] Nucleoprotein translocates to the plasma membrane [Homo sapiens] [Reaction:9717658] SARS-CoV-2 N binds DDX58 [Homo sapiens] [Reaction:9729437] SARS-CoV-2 N binds to TRIM25 [Homo sapiens] [Reaction:9729454] SARS-CoV-2 N protein binds STAT1, STAT2 [Homo sapiens] [Reaction:9729481] SARS-CoV-2 N binds to G3BP1,G3BP2 [Homo sapiens] [Reaction:9729500] SARS-CoV-2 N binds to 14-3-3 proteins [Homo sapiens] [Reaction:9755734] SARS-CoV-2 N binds IKBKB [Homo sapiens]
(updatedInstance) [_UpdateTracker:9776209] Update Tracker - [Reaction:9694363] Dimerisation of nucleoprotein - v77:[add_removeInput] [_UpdateTracker:9776453] Update Tracker - [Reaction:9694363] Dimerisation of nucleoprotein - v76:[addLiteratureReference]
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