Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person 3CLp forms a homodimer

Class:IdReaction:9694333
_displayName3CLp forms a homodimer
_doReleaseTRUE
_timestamp2022-04-29 20:03:21
authored[InstanceEdit:9696945] Stephan, Ralf, 2020-07-30
compartment[Compartment:70101] cytosol
created[InstanceEdit:9694660] Cook, Justin, 2020-07-07
disease[Disease:9683912] COVID-19
edited[InstanceEdit:9698832] Stephan, Ralf, 2020-08-28
input[DefinedSet:9694748] nsp5 [cytosol] [Severe acute respiratory syndrome coronavirus 2]
[DefinedSet:9694748] nsp5 [cytosol] [Severe acute respiratory syndrome coronavirus 2]
isChimericFALSE
literatureReference[LiteratureReference:9696988] Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
[LiteratureReference:9762499] Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300
modified[InstanceEdit:9697017] Stephan, Ralf, 2020-08-04
[InstanceEdit:9697028] Gillespie, Marc E, 2020-08-04
[InstanceEdit:9698635] Cook, Justin, 2020-08-27
[InstanceEdit:9698833] Stephan, Ralf, 2020-08-30
[InstanceEdit:9699043] Gillespie, Marc E, 2020-09-09
[InstanceEdit:9762500] Stephan, Ralf, 2022-01-26
[InstanceEdit:9763984] Orlic-Milacic, Marija, 2022-02-08
[InstanceEdit:9773094] Gillespie, Marc E, 2022-04-29
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name3CLp forms a homodimer
output[Complex:9694407] 3CLp dimer [cytosol] [Severe acute respiratory syndrome coronavirus 2]
precedingEvent
relatedSpecies[Species:9681683] Severe acute respiratory syndrome coronavirus 2
releaseDate2020-09-15
reviewed[InstanceEdit:9699044] Acencio, Marcio Luis, 2020-09-09
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9694960] R-HSA-9694333.4
summation[Summation:9694707] SARS-Cov-2 main protease forms a tight dimer. Dimerization ...
(hasEvent)[Pathway:9694301] Maturation of replicase proteins [Homo sapiens]
(precedingEvent)[Reaction:9694441] 3CLp cleaves pp1a [Homo sapiens]
[Reaction:9694551] 3CLp cleaves nsp6-11 [Homo sapiens]
[BlackBoxEvent:9694592] 3CLp dimer binds 3CLp inhibitors [Homo sapiens]
[Reaction:9694732] 3CLp cleaves pp1ab [Homo sapiens]
[Reaction:9729704] SARS-CoV-2 3CLpro dimer cleaves TAB1 [Homo sapiens]
[Reaction:9729741] SARS-CoV-2 3CLpro dimer cleaves NLRP12 [Homo sapiens]
[Reaction:9730501] SARS-CoV-2 3CLpro dimer binds to STING [Homo sapiens]
(updatedInstance)[_UpdateTracker:9774966] Update Tracker - [Reaction:9694333] 3CLp forms a homodimer - v80:[addLiteratureReference, modifyText]
[Change default viewing format]
No pathways have been reviewed or authored by 3CLp forms a homodimer (9694333)