Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Based on studies in Drosophila, RAP1GDS1, an orthologue of D...

Class:IdSummation:9693764
_displayNameBased on studies in Drosophila, RAP1GDS1, an orthologue of D...
_timestamp2020-07-15 11:43:54
created[InstanceEdit:9693761] Orlic-Milacic, Marija, 2020-07-06
literatureReference[LiteratureReference:9693763] Vimar Is a Novel Regulator of Mitochondrial Fission through Miro
modified[InstanceEdit:9695622] Orlic-Milacic, Marija, 2020-07-15
textBased on studies in Drosophila, RAP1GDS1, an orthologue of Drosophila Vimar, is a mitochondrial outer membrane-bound atypical guanine nucleotide exchange factor (GEF) that activates mitochondria-associated atypical RHO GTPase RHOT1, an orthologue of Drosophila Miro, by catalyzing GDP to GTP exchange, resulting in formation of the active RHOT1:GTP complex (Ding et al. 2016).
(summation)[Reaction:9018817] RHOT1 GEFs activate RHOT1 [Homo sapiens]
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No pathways have been reviewed or authored by Based on studies in Drosophila, RAP1GDS1, an orthologue of D... (9693764)