Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC

Class:Id	Reaction:9693590
_displayName	SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC
_doRelease	TRUE
_timestamp	2022-08-18 02:12:45
authored	[InstanceEdit:9692648] Shamovsky, Veronica, 2020-06-25
compartment	[Compartment:70101] cytosol [Compartment:9684675] double membrane vesicle viral factory outer membrane
created	[InstanceEdit:9693591] Shamovsky, Veronica, 2020-07-03
edited	[InstanceEdit:9796665] Shamovsky, Veronica, 2022-08-11
inferredFrom	[Reaction:9754745] IFIH1:TKFC binds SARS-CoV-2 dsRNA intermediates [Homo sapiens]
input	[DefinedSet:9693595] SARS-CoV-1 dsRNA with poly(U)-contaiining (-) strand [double membrane vesicle viral factory outer membrane] [Human SARS coronavirus] [Complex:918203] IFIH1:TKFC [cytosol] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9707761] Shamovsky, Veronica, 2020-11-19 [InstanceEdit:9710711] Shamovsky, Veronica, 2021-01-05 [InstanceEdit:9713614] Shamovsky, Veronica, 2021-01-27 [InstanceEdit:9796177] Shamovsky, Veronica, 2022-08-05 [InstanceEdit:9796527] Shamovsky, Veronica, 2022-08-10 [InstanceEdit:9796648] Shamovsky, Veronica, 2022-08-11 [InstanceEdit:9796657] Shamovsky, Veronica, 2022-08-11 [InstanceEdit:9815484] Shamovsky, Veronica, 2022-08-18 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC dsRNA binds to MDA5
output	[EntityWithAccessionedSequence:918185] TKFC [cytosol] [Homo sapiens] [Complex:9693588] SARS-CoV-1 dsRNA intermediates:IFIH1 [double membrane vesicle viral factory outer membrane] [Homo sapiens]
regulatedBy	[NegativeRegulation:9693594] Negative regulation by 'RTC [double membrane vesicle viral factory outer membrane]'
regulationReference	[RegulationReference:9691372] Negative regulation by 'RTC [double membrane vesicle viral factory outer membrane]' Mutational analysis of the SARS virus Nsp15 endoribonuclease: identification of residues affecting hexamer formation
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2022-09-14
reviewed	[InstanceEdit:9713569] D'Eustachio, Peter, 2021-01-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9693600] R-HSA-9693590.2
summation	[Summation:9693585] This severe acute respiratory syndrome coronavirus 1 (SARS-C...
(hasEvent)	[Pathway:9692916] SARS-CoV-1 activates/modulates innate immune responses [Homo sapiens] [Pathway:9711037] Microbial regulators of DDX58/IFIH1 signaling [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by SARS-CoV-1 dsRNA intermediates bind IFIH1:TKFC (9693590)