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Details on Person FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

Class:IdLiteratureReference:9693335
_displayNameFDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
_timestamp2020-07-01 04:17:32
author[Person:9693329] Hu, Jun Jacob
[Person:5228415] Liu, Xing
[Person:9693330] Xia, Shiyu
[Person:9647652] Zhang, Zhibin
[Person:9622537] Zhang, Ying
[Person:9693318] Zhao, Jingxia
[Person:9647687] Ruan, Jianbin
[Person:9693323] Luo, Xuemei
[Person:9693327] Lou, Xiwen
[Person:9639122] Bai, Yang
[Person:9693321] Wang, Junhong
[Person:9693334] Hollingsworth, L Robert
[Person:9647623] Magupalli, Venkat Giri
[Person:2458348] Zhao, Li
[Person:8875234] Luo, Hongbo R
[Person:9693331] Kim, Justin
[Person:2453966] Lieberman, Judy
[Person:1237368] Wu, H
created[InstanceEdit:9693320] Shamovsky, Veronica, 2020-07-01
journalNat. Immunol.
pages736-745
pubMedIdentifier32367036
titleFDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
volume21
year2020
(literatureReference)[Reaction:9693324] Disulfiram covalently modifies Cys191 in GSDMD [Homo sapiens]
[Summation:9693328] During inflammation, the inflammatory caspase‑1 (CASP1) can ...
[RegulationReference:9693343] Negative regulation by 'dithiocarb-C191-GSDMD(1-275) [cytosol]' FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
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