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Details on Person Expression of SRY in testis differentiation

Class:Id	BlackBoxEvent:9692241
_displayName	Expression of SRY in testis differentiation
_doRelease	TRUE
_timestamp	2020-10-29 04:45:25
authored	[InstanceEdit:9692203] May, Bruce, 2020-06-22
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9692233] May, Bruce, 2020-06-22
edited	[InstanceEdit:9692203] May, Bruce, 2020-06-22
inferredFrom	[BlackBoxEvent:9692260] Expression of Sry in testis differentiation [Mus musculus]
input	[EntityWithAccessionedSequence:9692246] SRY gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9692254] A GATA4/WT1 cooperation regulates transcription of genes required for mammalian sex determination and differentiation [LiteratureReference:9692232] The human sex-determining gene SRY is a direct target of WT1 [LiteratureReference:9692223] Steroidogenic factor-1 contributes to the cyclic-adenosine monophosphate down-regulation of human SRY gene expression
modified	[InstanceEdit:9692985] May, Bruce, 2020-06-28 [InstanceEdit:9696121] May, Bruce, 2020-07-18 [InstanceEdit:9705707] May, Bruce, 2020-10-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of SRY in testis differentiation
output	[EntityWithAccessionedSequence:5627706] SRY [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9692250] WT1, NR5A1 (SF1), GATA4, ZFPM2 bind the SRY gene [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9692216] Positive gene expression regulation by 'WT1:NR5A1:GATA4:ZFPM2:SRY gene [nucleoplasm]'
regulationReference	[RegulationReference:9696120] Positive gene expression regulation by 'WT1:NR5A1:GATA4:ZFPM2:SRY gene [nucleoplasm]' The human sex-determining gene SRY is a direct target of WT1
releaseDate	2020-12-08
reviewed	[InstanceEdit:9705697] Kanai, Yoshiakira, 2020-10-29 [InstanceEdit:9705699] Imaimatsu, Kenya, 2020-10-29
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9692278] R-HSA-9692241.2
summation	[Summation:9692980] In the gonadal ridge (genital ridge), the SRY gene is transc...
(hasEvent)	[Pathway:9690406] Transcriptional regulation of testis differentiation [Homo sapiens]
(precedingEvent)	[Reaction:9690414] SRY and NR5A1 (SF1) bind SOX9 gene [Homo sapiens]
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No pathways have been reviewed or authored by Expression of SRY in testis differentiation (9692241)