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Details on Person Sox9 and Nr5a1 (Sf1) bind the Amh gene

Class:Id	Reaction:9692157
_displayName	Sox9 and Nr5a1 (Sf1) bind the Amh gene
_doRelease	TRUE
_timestamp	2020-10-29 04:48:06
authored	[InstanceEdit:9692160] May, Bruce, 2020-06-15
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9692158] May, Bruce, 2020-06-20
edited	[InstanceEdit:9692160] May, Bruce, 2020-06-15
input	[EntityWithAccessionedSequence:9692085] Amh gene [nucleoplasm] [Mus musculus] [EntityWithAccessionedSequence:8985368] Sox9 [nucleoplasm] [Mus musculus] [EntityWithAccessionedSequence:9690381] Nr5a1 [nucleoplasm] [Mus musculus] [EntityWithAccessionedSequence:9692183] Gata4 [nucleoplasm] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9690372] The sex-determining factors SRY and SOX9 regulate similar target genes and promote testis cord formation during testicular differentiation [LiteratureReference:9690893] In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures [LiteratureReference:9692197] Nuclear receptor steroidogenic factor 1 regulates the m�llerian inhibiting substance gene: a link to the sex determination cascade [LiteratureReference:9692184] Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the M�llerian inhibiting substance promoter [LiteratureReference:9696126] In Vivo Ablation of the Conserved GATA-Binding Motif in the Amh Promoter Impairs Amh Expression in the Male Mouse
modified	[InstanceEdit:9692203] May, Bruce, 2020-06-22 [InstanceEdit:9693012] May, Bruce, 2020-06-28 [InstanceEdit:9696128] May, Bruce, 2020-07-18 [InstanceEdit:9705707] May, Bruce, 2020-10-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Sox9 and Nr5a1 (Sf1) bind the Amh gene
output	[Complex:9692113] Sox9:Nr5a1:Gata4:Amh gene [nucleoplasm] [Mus musculus]
releaseDate	2020-12-08
reviewed	[InstanceEdit:9705697] Kanai, Yoshiakira, 2020-10-29 [InstanceEdit:9705699] Imaimatsu, Kenya, 2020-10-29
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9692169] R-MMU-9692157.2
summation	[Summation:9692992] Sox9, Nr5a1 (SF1), and Gata4 bind the promoter of the Amh ge...
(inferredFrom)	[Reaction:9692135] SOX9, NR5A1 (SF1), and GATA4 bind the AMH gene [Homo sapiens]
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No pathways have been reviewed or authored by Sox9 and Nr5a1 (Sf1) bind the Amh gene (9692157)