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Details on Person Expression of DMRT1 in testis differentiation

Class:Id	BlackBoxEvent:9690877
_displayName	Expression of DMRT1 in testis differentiation
_doRelease	TRUE
_timestamp	2020-10-29 04:43:28
authored	[InstanceEdit:9690407] May, Bruce, 2020-05-31
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9690891] May, Bruce, 2020-06-06
edited	[InstanceEdit:9690407] May, Bruce, 2020-05-31
inferredFrom	[BlackBoxEvent:9690898] Expression of Dmrt1 in testis differentiation [Mus musculus]
input	[EntityWithAccessionedSequence:9690876] DMRT1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9690893] In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures [LiteratureReference:9693675] Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entry
modified	[InstanceEdit:9692295] May, Bruce, 2020-06-22 [InstanceEdit:9693012] May, Bruce, 2020-06-28 [InstanceEdit:9693684] May, Bruce, 2020-07-05 [InstanceEdit:9705707] May, Bruce, 2020-10-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Expression of DMRT1 in testis differentiation
output	[EntityWithAccessionedSequence:9690892] DMRT1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9690896] SOX9 and GATA4 bind the DMRT1 gene [Homo sapiens] [BlackBoxEvent:9690404] Expression of SOX9 in testis differentiation [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9690874] Positive gene expression regulation by 'SOX9:GATA4:DMRT1 gene [nucleoplasm]'
regulationReference	[RegulationReference:9690870] Positive gene expression regulation by 'SOX9:GATA4:DMRT1 gene [nucleoplasm]' In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures
releaseDate	2020-12-08
reviewed	[InstanceEdit:9705697] Kanai, Yoshiakira, 2020-10-29 [InstanceEdit:9705699] Imaimatsu, Kenya, 2020-10-29
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9690917] R-HSA-9690877.2
summation	[Summation:9693010] In the gonadal ridge, the DMRT1 gene is transcribed to yield...
(hasEvent)	[Pathway:9690406] Transcriptional regulation of testis differentiation [Homo sapiens]
(precedingEvent)	[Reaction:9692228] DMRT1 binds the SOX9 gene [Homo sapiens] [Reaction:9692236] DMRT1 binds the FOXL2 gene [Homo sapiens] [Reaction:9692297] DMRT1 binds the WNT4 gene [Homo sapiens]
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No pathways have been reviewed or authored by Expression of DMRT1 in testis differentiation (9690877)