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Details on Person Negative regulation by 'FKBP1A:sirolimus [cytosol]' Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression
| Class:Id | RegulationReference:9690474 |
|---|---|
| _displayName | Negative regulation by 'FKBP1A:sirolimus [cytosol]' Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression |
| _timestamp | 2020-06-01 14:24:31 |
| created | [InstanceEdit:9690476] Jassal, Bijay, 2020-06-01 |
| literatureReference | [LiteratureReference:9690460] Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression [LiteratureReference:9690464] Sirolimus: its discovery, biological properties, and mechanism of action |
| regulation | [NegativeRegulation:9690475] Negative regulation by 'FKBP1A:sirolimus [cytosol]' |
| (regulationReference) | [Reaction:165692] Phosphorylation of 4E-BP1 by activated mTORC1 [Homo sapiens] [Reaction:165718] mTORC1 phosphorylation of RPS6KB1 (S6K) [Homo sapiens] |
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No pathways have been reviewed or authored by Negative regulation by 'FKBP1A:sirolimus [cytosol]' Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression (9690474)
