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Details on Person FLT3 D600_L601insMGMGGECNPGRQ [plasma membrane]

Class:Id	EntityWithAccessionedSequence:9690076
_displayName	FLT3 D600_L601insMGMGGECNPGRQ [plasma membrane]
_timestamp	2020-05-25 19:35:38
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9690085] Rothfels, Karen, 2020-05-25
disease	[Disease:1500689] cancer [Disease:9630839] acute myeloid leukemia
endCoordinate	993
hasModifiedResidue	[FragmentReplacedModification:9690081] Replacement of residues 600 to 601 by DMGMGGECNPGRQL
literatureReference	[LiteratureReference:9683350] Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product
name	FLT3 D600_L601insMGMGGECNPGRQ STK-1 Mt6
referenceEntity	[ReferenceGeneProduct:54914] UniProt:P36888 FLT3 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9690090] R-HSA-9690076.1
startCoordinate	27
(hasComponent)	[Complex:9691982] FLT3 D600_L601insMGMGGECNPGRQ dimer [plasma membrane] [Homo sapiens]
(hasMember)	[CandidateSet:9691152] juxtamembrane domain mutants of FLT3 [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by FLT3 D600_L601insMGMGGECNPGRQ [plasma membrane] (9690076)