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Details on Person Jassal, Bijay, 2020-05-21

Class:IdInstanceEdit:9689679
_displayNameJassal, Bijay, 2020-05-21
_timestamp2020-05-21 13:03:20
author[Person:73447] Jassal, Bijay
dateTime2020-05-21 13:03:12
(created)[LiteratureReference:9689678] Three-dimensional structures of a humanized anti-IFN-gamma Fab (HuZAF) in two crystal forms
[Reaction:9689680] IFNG dimer binds IFNG inhibitors [Homo sapiens]
[ReferenceTherapeutic:9689681] emapalumab [Guide to Pharmacology:9295]
[LiteratureReference:9689682] Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice
[LiteratureReference:9689683] Fontolizumab, a humanised anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease
[Summation:9689684] Interferons (IFNs) are cytokines that play a central role in...
[Disease:9689685] hemophagocytic lymphohistiocytosis
[NegativeRegulation:9689686] Negative regulation by 'IFNG dimer:IFNG inhibitors [extracellular region]'
[LiteratureReference:9689687] Treatment of refractory hemophagocytic lymphohistiocytosis with emapalumab despite severe concurrent infections
[Complex:9689688] IFNG dimer:IFNG inhibitors [extracellular region] [Homo sapiens]
List all 20 refering instances
(modified)[Complex:873823] IFNG dimer [extracellular region] [Homo sapiens]
[Reaction:873926] IFNG dimer binds IFNGR [Homo sapiens]
[PathwayDiagram:877288] Diagram of Interferon gamma signaling
[Pathway:877300] Interferon gamma signaling [Homo sapiens]
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No pathways have been reviewed or authored by Jassal, Bijay, 2020-05-21 (9689679)