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Details on Person Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
| Class:Id | LiteratureReference:9689630 |
| _displayName | Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation |
| _timestamp | 2020-05-21 01:18:13 |
| author | [Person:9686106] Rogers, Corey [Person:9689627] Erkes, Dan A [Person:9689628] Nardone, Alexandria [Person:9689631] Aplin, Andrew E [Person:141890] Fernandes-Alnemri, T [Person:141891] Alnemri, ES |
| created | [InstanceEdit:9689629] Shamovsky, Veronica, 2020-05-21 |
| journal | Nat Commun |
| pages | 1689 |
| pubMedIdentifier | 30976076 |
| title | Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation |
| volume | 10 |
| year | 2019 |
| (literatureReference) | [Reaction:9710254] GSDME oligomerizes [Homo sapiens] [Reaction:9710353] GSDMD (1-275) binds cardiolipin [Homo sapiens] [Reaction:9710354] GSDME (1-270) binds cardiolipin [Homo sapiens] [Summation:9647646] Gasdermin E (GSDME, also known as DFNA5) was identified as a... [Summation:9647668] Pyroptosis is a form of lytic inflammatory programmed cell d... [Summation:9647673] The N-terminal domain of gasdermin D (GSDMD(1-275), also kno... [Summation:9710258] The N‑terminal fragment of gasdermin E (GSDME(1-270)) produc... [Summation:9710361] Gasdermin D (GSDMD) is cleaved by inflammatory caspases (CAS... [Summation:9710363] Gasdermin E (GSDME) is cleaved by caspase 3 (CASP3) at D270 ... [RegulationReference:9710341] Positive regulation by 'GSDME:cardiolipin [mitochondrial outer membrane]' Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation |
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