Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person MLKL Requires the Inositol Phosphate Code to Execute Necroptosis

Class:IdLiteratureReference:9687641
_displayNameMLKL Requires the Inositol Phosphate Code to Execute Necroptosis
_timestamp2020-05-12 06:31:35
author[Person:9687634] Dovey, Cole M
[Person:9687640] Diep, Jonathan
[Person:9687629] Clarke, Bradley P
[Person:9687624] Hale, Andrew T
[Person:9687631] McNamara, Dan E
[Person:9687479] Guo, Hongyan
[Person:9687628] Brown, Nathaniel W
[Person:9687626] Cao, Jennifer Yinuo
[Person:9687635] Grace, Christy R
[Person:5364128] Gough, Peter J
[Person:5364194] Bertin, John
[Person:9031572] Dixon, Scott J
[Person:9687623] Fiedler, Dorothea
[Person:5364063] Mocarski, Edward S
[Person:5364087] Kaiser, William J
[Person:5661325] Moldoveanu, Tudor
[Person:176513] York, JD
[Person:5624212] Carette, Jan E
created[InstanceEdit:9687619] Shamovsky, Veronica, 2020-05-12
journalMol. Cell
pages936-948.e7
pubMedIdentifier29883610
titleMLKL Requires the Inositol Phosphate Code to Execute Necroptosis
volume70
year2018
(literatureReference)[Summation:5357788] Mixed lineage kinase domain-like protein (MLKL) was found to...
[Summation:9687637] Metabolites of the inositol phosphate (IP) pathway I(1,3,4,6...
[Reaction:9687638] MLKL binds IP4, IP5 and IP6 [Homo sapiens]
[RegulationReference:9692644] Positive regulation by 'p-S-RIPK1:p-S199,227-RIPK3 oligomer:4xMLKL:IP6,IP5, IP4 [cytosol]' Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites
[Change default viewing format]
No pathways have been reviewed or authored by MLKL Requires the Inositol Phosphate Code to Execute Necroptosis (9687641)