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Details on Person Fusion and Release of SARS-CoV-1 Nucleocapsid

Class:Id	Reaction:9686699
_displayName	Fusion and Release of SARS-CoV-1 Nucleocapsid
_doRelease	TRUE
_timestamp	2022-04-29 20:03:48
authored	[InstanceEdit:9686671] Gillespie, Marc E, 2020-05-05
compartment	[Compartment:24337] endocytic vesicle membrane
created	[InstanceEdit:9686727] Gillespie, Marc E, 2020-05-05
disease	[Disease:9678120] severe acute respiratory syndrome
edited	[InstanceEdit:9690126] Gillespie, Marc E, 2020-05-26
input	[Complex:9686703] S1:S2:M:E:encapsidated SARS coronavirus genomic RNA: 7a:O-glycosyl 3a tetramer [endocytic vesicle lumen] [Human SARS coronavirus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9687536] Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes
modified	[InstanceEdit:9687446] D'Eustachio, Peter, 2020-05-08 [InstanceEdit:9687566] Gillespie, Marc E, 2020-05-10 [InstanceEdit:9689462] D'Eustachio, Peter, 2020-05-19 [InstanceEdit:9689807] D'Eustachio, Peter, 2020-05-21 [InstanceEdit:9690209] Gillespie, Marc E, 2020-05-27 [InstanceEdit:9697028] Gillespie, Marc E, 2020-08-04 [InstanceEdit:9773094] Gillespie, Marc E, 2022-04-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Fusion and Release of SARS-CoV-1 Nucleocapsid
output	[Complex:9686705] S1:S2:M:E: 7a:O-glycosyl 3a tetramer [endocytic vesicle membrane] [Human SARS coronavirus] [Complex:9686697] encapsidated SARS coronavirus genomic RNA (plus strand) [cytosol] [Human SARS coronavirus]
precedingEvent	[Reaction:9686710] Cleavage of S protein into S1:S2 [Homo sapiens] [Reaction:9686711] Endocytosis of SARS-CoV-1 Virion [Homo sapiens] [Reaction:9686731] TMPRSS2 Mediated SARS-CoV-1 Spike Protein Cleavage and Endocytosis [Homo sapiens] [Reaction:9678128] Spike glycoprotein of SARS coronavirus binds ACE2 on host cell [Homo sapiens]
regulatedBy	[PositiveRegulation:9687542] Positive regulation by 'VCP [cytosol]'
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2020-06-10
reviewed	[InstanceEdit:9690206] Acencio, Marcio Luis, Mazein, Alexander, 2020-05-27
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9686741] R-HSA-9686699.4
summation	[Summation:9687554] The SARS-CoV-1 nucleocapsid is released from the host cell e...
(hasEvent)	[Pathway:9678110] Attachment and Entry [Homo sapiens]
(inferredFrom)	[Reaction:9694689] Fusion and Release of SARS-CoV-2 Nucleocapsid [Homo sapiens]
(precedingEvent)	[Reaction:9686709] Uncoating of SARS-CoV-1 Genome [Homo sapiens]
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No pathways have been reviewed or authored by Fusion and Release of SARS-CoV-1 Nucleocapsid (9686699)