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Details on Person Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
| Class:Id | LiteratureReference:9686453 |
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| _displayName | Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis |
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| _timestamp | 2020-05-01 03:35:01 |
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| author | [Person:9686454] Petrie, Emma J
[Person:9686476] Sandow, Jarrod J
[Person:9686466] Jacobsen, Annette V
[Person:9676803] Smith, Brian J
[Person:9686451] Griffin, Michael D W
[Person:5364117] Lucet, Isabelle S
[Person:9686473] Dai, Weiwen
[Person:5364098] Young, Samuel N
[Person:9686126] Tanzer, Maria C
[Person:9686478] Wardak, Ahmad
[Person:9686456] Liang, Lung-Yu
[Person:9686460] Cowan, Angus D
[Person:5364228] Hildebrand, Joanne M
[Person:9686445] Kersten, Wilhelmus J A
[Person:9686477] Lessene, Guillaume
[Person:141939] Silke, J
[Person:5364146] Czabotar, Peter E
[Person:5364137] Webb, Andrew I
[Person:5364059] Murphy, James M |
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| created | [InstanceEdit:9686457] Shamovsky, Veronica, 2020-05-01 |
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| journal | Nat Commun |
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| pages | 2422 |
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| pubMedIdentifier | 29930286 |
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| title | Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis |
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| volume | 9 |
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| year | 2018 |
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| (literatureReference) | [RegulationReference:9692647] Negative regulation by '(p-S-RIPK1:p-S199,227-RIPK3) oligomer:4x(MLKL:ATP) [cytosol]' Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
[Polymerisation:5357927] MLKL oligomerizes [Homo sapiens]
[Pathway:5675482] Regulation of necroptotic cell death [Homo sapiens]
[Reaction:9687625] ATP binds MLKL [Homo sapiens]
[Summation:5357754] Exogenous stimuli provoke assembly of the receptor-interacti...
[Summation:5357788] Mixed lineage kinase domain-like protein (MLKL) was found to...
[Summation:5357947] Receptor-interacting serine/threonine-protein kinase 3 (RIPK...
[Summation:9687636] Recombinant pseudokinase mixed lineage kinase domain-like (M...
[Summation:9793449] Exogenous stimuli provoke assembly of the receptor-interacti...
[Polymer:5357857] p-T357,S358-MLKL oligomer [cytosol] [Homo sapiens] |
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