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Details on Person Shamovsky, Veronica, 2020-04-29

Class:Id	InstanceEdit:9686281
_displayName	Shamovsky, Veronica, 2020-04-29
_timestamp	2020-04-29 05:01:46
author	[Person:429259] Shamovsky, Veronica
dateTime	2020-04-29 05:01:36
(created)	[Polymerisation:9686277] NLRP3 oligomerizes [Homo sapiens] [Complex:9686278] MAVS:TOMM70:NLRP3 oligomer [mitochondrial outer membrane] [Homo sapiens] [EntityWithAccessionedSequence:9686279] O-glycosyl 3a [cytosol] [Human SARS coronavirus] [Pathway:9686280] NLRP3 inflammasome activation upon viral infection [Homo sapiens] [RegulationReference:9686282] Positive regulation by 'SARS CoV 3a:NLRP3 oligomer:MAVS:TRAF3:PYCARD [mitochondrial outer membrane]' Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC [StableIdentifier:9686283] R-COV-9686279.15 [StableIdentifier:9686284] R-HSA-9686278.1 [StableIdentifier:9686285] R-HSA-9686277.1 [StableIdentifier:9686286] R-HSA-9686280.1
(modified)	[Pathway:844456] The NLRP3 inflammasome [Homo sapiens] [Complex:9685242] 3a:NLRP3 oligomer:MAVS:TRAF3:PYCARD [mitochondrial outer membrane] [Homo sapiens] [BlackBoxEvent:9685243] TRAF3 polyubiquitinates PYCARD [Homo sapiens] [Reaction:9685246] MAVS recruits TRAF3 [Homo sapiens] [Reaction:9685255] NLRP3:MAVS:TRAF3 recruits PYCARD (ASC) [Homo sapiens] [Complex:9685256] NLRP3:MAVS:TOMM70 [mitochondrial outer membrane] [Homo sapiens] [Reaction:9685270] NLRP3:SUGT1:HSP90 binds MAVS [Homo sapiens] [PositiveRegulation:9685279] Positive regulation by 'SARS CoV 3a:NLRP3 oligomer:MAVS:TRAF3:PYCARD [mitochondrial outer membrane]' [Summation:9685280] Open reading frame 8b (orf8b) of Severe Acute Respiratory Sy... [Reaction:9685281] SARS-CoV-1 3a binds TRAF3 within NLRP3 inflammasome [Homo sapiens]
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No pathways have been reviewed or authored by Shamovsky, Veronica, 2020-04-29 (9686281)