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Details on Person NLRP3 oligomerizes

Class:Id	Polymerisation:9686277
_displayName	NLRP3 oligomerizes
_timestamp	2021-01-18 17:03:20
catalystActivity	[CatalystActivity:9712362] ATP hydrolysis activity of NLRP3:MAVS:TOMM70 [mitochondrial outer membrane]
compartment	[Compartment:17906] mitochondrial outer membrane [Compartment:70101] cytosol
created	[InstanceEdit:9686281] Shamovsky, Veronica, 2020-04-29
input	[Complex:9685256] NLRP3:MAVS:TOMM70 [mitochondrial outer membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9708063] The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity
modified	[InstanceEdit:9708089] Shamovsky, Veronica, 2020-11-24 [InstanceEdit:9708914] Shamovsky, Veronica, 2020-12-03 [InstanceEdit:9712304] Shamovsky, Veronica, 2021-01-18
name	NLRP3 oligomerizes
output	[Complex:9686278] MAVS:TOMM70:NLRP3 oligomer [mitochondrial outer membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29372] Pi [cytosol]
precedingEvent	[Reaction:9685270] NLRP3:SUGT1:HSP90 binds MAVS [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9686285] R-HSA-9686277.1
summation	[Summation:9708090] The mitochondrial antiviral signaling protein (MAVS) is acti...
(hasEvent)	[Pathway:9686280] NLRP3 inflammasome activation upon viral infection [Homo sapiens]
(precedingEvent)	[Reaction:9685246] MAVS recruits TRAF3 [Homo sapiens]
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No pathways have been reviewed or authored by NLRP3 oligomerizes (9686277)