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Details on Person CASP5 binds LPS micelles

Class:IdReaction:9686100
_displayNameCASP5 binds LPS micelles
_doReleaseTRUE
_timestamp2025-08-18 13:53:31
authored[InstanceEdit:9947804] Shamovsky, Veronica, 2025-05-14
compartment[Compartment:70101] cytosol
created[InstanceEdit:9686081] Shamovsky, Veronica, 2020-04-28
edited[InstanceEdit:9963520] Shamovsky, Veronica, 2025-08-14
input[SimpleEntity:9686105] LPS micelles [bacterial outer membrane vesicle]
[EntityWithAccessionedSequence:9686132] CASP5(1-434) [cytosol] [Homo sapiens]
internalReviewed[InstanceEdit:9960500] Matthews, Lisa, 2025-07-09
isChimericFALSE
literatureReference[LiteratureReference:9652838] Inflammatory caspases are innate immune receptors for intracellular LPS
[LiteratureReference:9947828] Membrane vesicles from Pseudomonas aeruginosa activate the noncanonical inflammasome through caspase-5 in human monocytes
[LiteratureReference:9647669] Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
[LiteratureReference:9686131] Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes
modified[InstanceEdit:9947975] Shamovsky, Veronica, 2025-05-14
[InstanceEdit:9953148] Shamovsky, Veronica, 2025-05-28
[InstanceEdit:9958641] Shamovsky, Veronica, 2025-06-24
[InstanceEdit:9960494] Shamovsky, Veronica, 2025-07-14
[InstanceEdit:9963543] Shamovsky, Veronica, 2025-08-14
[InstanceEdit:9963953] Shamovsky, Veronica, 2025-08-18
nameCASP5 binds LPS micelles
output[Complex:9686087] CASP5(1-434):LPS micelles [cytosol] [Homo sapiens]
releaseDate2025-09-18
reviewed[InstanceEdit:9963135] Shi, Xuyan, 2025-08-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9686147] R-HSA-9686100.1
summation[Summation:9953138] Intracellular bacterial lipopolysaccharide (LPS) binds to th...
(hasEvent)[Pathway:9948011] CASP5 inflammasome assembly [Homo sapiens]
(precedingEvent)[Polymerisation:9947937] CASP5 dimerizes [Homo sapiens]
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No pathways have been reviewed or authored by CASP5 binds LPS micelles (9686100)