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Details on Person Production of polyprotein fragments (so called replicase pro...

Class:Id	Summation:9684318
_displayName	Production of polyprotein fragments (so called replicase pro...
_timestamp	2020-04-21 02:30:55
created	[InstanceEdit:9684359] Stephan, Ralf, 2020-04-21
literatureReference	[LiteratureReference:9684331] SARS-CoV 3CL protease cleaves its C-terminal autoprocessing site by novel subsite cooperativity [LiteratureReference:9684306] Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity [LiteratureReference:9684300] Localization and membrane topology of coronavirus nonstructural protein 4: involvement of the early secretory pathway in replication
modified	[InstanceEdit:9684393] Stephan, Ralf, 2020-04-21
text	Production of polyprotein fragments (so called replicase proteins) involves the repeated autocleavage of the polyprotein, liberating the two endopeptidases that finally cleave all fragments efficiently. Only nsp3 and nsp4 are post-translationally modified, they are glycosylated (Muramatsu et al, 2015; Harcourt et al, 2004; Oostra et al, 2007)
(summation)	[Pathway:9684325] Maturation of replicase proteins [Homo sapiens]
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No pathways have been reviewed or authored by Production of polyprotein fragments (so called replicase pro... (9684318)