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Details on Person ATP1A:ATP1B:FXYD binds cardiac glycosides

Class:IdReaction:9684068
_displayNameATP1A:ATP1B:FXYD binds cardiac glycosides
_doReleaseTRUE
_timestamp2020-05-29 10:22:18
authored[InstanceEdit:9684071] Jassal, Bijay, 2020-04-20
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:9684071] Jassal, Bijay, 2020-04-20
definitionInhibition
edited[InstanceEdit:9684071] Jassal, Bijay, 2020-04-20
input[DefinedSet:9684063] cardiac glycosides [extracellular region]
[Complex:936770] ATP1A:ATP1B:FXYD [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9684058] The basic mechanism of inotropic action of digitalis glycosides
[LiteratureReference:9690292] Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1
[LiteratureReference:9684075] Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na+,K+-ATPase Blocks HIV-1 Infection
[LiteratureReference:9690291] Selectivity of digitalis glycosides for isoforms of human Na,K-ATPase
[LiteratureReference:9690305] Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase
modified[InstanceEdit:9684091] Jassal, Bijay, 2020-04-20
[InstanceEdit:9685756] Jassal, Bijay, 2020-04-27
[InstanceEdit:9687446] D'Eustachio, Peter, 2020-05-08
[InstanceEdit:9688550] Jassal, Bijay, 2020-05-14
[InstanceEdit:9688754] Jassal, Bijay, 2020-05-14
[InstanceEdit:9690290] Jassal, Bijay, 2020-05-29
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameATP1A:ATP1B:FXYD binds cardiac glycosides
output[Complex:9684072] ATP1A:ATP1B:FXYD:cardiac glycosides [plasma membrane] [Homo sapiens]
releaseDate2020-06-10
reviewed[InstanceEdit:9688552] Shoichet, Brian, 2020-05-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9684083] R-HSA-9684068.3
summation[Summation:9684059] Cardiac glycosides are a class of organic compounds that inc...
(hasEvent)[Pathway:936837] Ion transport by P-type ATPases [Homo sapiens]
[Pathway:5578775] Ion homeostasis [Homo sapiens]
[Pathway:9679191] Potential therapeutics for SARS [Homo sapiens]
(updatedInstance)[_UpdateTracker:9776654] Update Tracker - [Reaction:9684068] ATP1A:ATP1B:FXYD binds cardiac glycosides - v74:[addLiteratureReference, add_removeInput, modifyText]
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No pathways have been reviewed or authored by ATP1A:ATP1B:FXYD binds cardiac glycosides (9684068)