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Details on Person Spike protein gets palmitoylated

Class:Id	Reaction:9683653
_displayName	Spike protein gets palmitoylated
_doRelease	TRUE
_timestamp	2025-02-05 09:45:59
authored	[InstanceEdit:9683645] Stephan, Ralf, 2020-04-08
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:9683729] Stephan, Ralf, 2020-04-17
disease	[Disease:9678120] severe acute respiratory syndrome
edited	[InstanceEdit:9689806] D'Eustachio, Peter, 2020-05-21
input	[EntityWithAccessionedSequence:9683608] trimmed N-glycan Spike [endoplasmic reticulum lumen] [Human SARS coronavirus] [SimpleEntity:9683736] palmitoyl-CoA [endoplasmic reticulum lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:9682993] Palmitoylation of SARS-CoV S protein is necessary for partitioning into detergent-resistant membranes and cell-cell fusion but not interaction with M protein
modified	[InstanceEdit:9686628] Stephan, Ralf, 2020-05-04 [InstanceEdit:9687446] D'Eustachio, Peter, 2020-05-08 [InstanceEdit:9689807] D'Eustachio, Peter, 2020-05-21 [InstanceEdit:9690134] D'Eustachio, Peter, 2020-05-26 [InstanceEdit:9697028] Gillespie, Marc E, 2020-08-04 [InstanceEdit:9773094] Gillespie, Marc E, 2022-04-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9937650] Stephan, Ralf, 2025-02-05
name	Spike protein gets palmitoylated
output	[SimpleEntity:162743] CoA-SH [endoplasmic reticulum lumen] [EntityWithAccessionedSequence:9683638] trimmed N-glycan-PALM-Spike [endoplasmic reticulum lumen] [Human SARS coronavirus]
precedingEvent	[Reaction:9683772] Trimmed spike protein binds to calnexin [Homo sapiens] [BlackBoxEvent:9683663] N-glycan trimming of Spike [Homo sapiens]
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2020-06-10
reviewed	[InstanceEdit:9690206] Acencio, Marcio Luis, Mazein, Alexander, 2020-05-27
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9683796] R-HSA-9683653.5
summation	[Summation:9682979] Two of the four cysteine-rich clusters of the SARS-CoV-1 spi...
(hasEvent)	[Pathway:9683686] Maturation of spike protein [Homo sapiens]
(precedingEvent)	[Reaction:9683719] Spike protein forms a homotrimer [Homo sapiens]
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No pathways have been reviewed or authored by Spike protein gets palmitoylated (9683653)