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Details on Person nsp16 binds nsp10

Class:Id	Reaction:9683429
_displayName	nsp16 binds nsp10
_doRelease	TRUE
_timestamp	2020-08-04 17:55:55
authored	[InstanceEdit:9686443] Orlic-Milacic, Marija, 2020-04-30
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9683423] Orlic-Milacic, Marija, 2020-04-15
disease	[Disease:9678120] severe acute respiratory syndrome
edited	[InstanceEdit:9687600] Orlic-Milacic, Marija, 2020-05-11
input	[EntityWithAccessionedSequence:9678289] pp1ab-nsp16 [cytosol] [Human SARS coronavirus] [DefinedSet:9682215] nsp10 [cytosol] [Human SARS coronavirus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9683422] In vitro reconstitution of SARS-coronavirus mRNA cap methylation [LiteratureReference:9682548] RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex [LiteratureReference:9683430] Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex [LiteratureReference:9683448] Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis [LiteratureReference:9683506] Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes [LiteratureReference:9683513] Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16 [LiteratureReference:9684045] Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex [LiteratureReference:9684873] Crystallization and diffraction analysis of the SARS coronavirus nsp10-nsp16 complex
modified	[InstanceEdit:9683450] Orlic-Milacic, Marija, 2020-04-15 [InstanceEdit:9683509] Orlic-Milacic, Marija, 2020-04-17 [InstanceEdit:9683514] Orlic-Milacic, Marija, 2020-04-17 [InstanceEdit:9684871] Stephan, Ralf, 2020-04-22 [InstanceEdit:9686647] D'Eustachio, Peter, 2020-05-04 [InstanceEdit:9687446] D'Eustachio, Peter, 2020-05-08 [InstanceEdit:9689807] D'Eustachio, Peter, 2020-05-21 [InstanceEdit:9690155] Orlic-Milacic, Marija, 2020-05-27 [InstanceEdit:9690209] Gillespie, Marc E, 2020-05-27 [InstanceEdit:9697028] Gillespie, Marc E, 2020-08-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	nsp16 binds nsp10
output	[Complex:9683433] nsp16:nsp10 [cytosol] [Human SARS coronavirus]
relatedSpecies	[Species:9678119] Human SARS coronavirus
releaseDate	2020-06-10
reviewed	[InstanceEdit:9690206] Acencio, Marcio Luis, Mazein, Alexander, 2020-05-27
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9683435] R-HSA-9683429.3
summation	[Summation:9683419] The non-structural protein 16 (nsp16) of the human SARS coro...
(hasEvent)	[Pathway:9683439] Assembly of the SARS-CoV-1 Replication-Transcription Complex (RTC) [Homo sapiens]
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No pathways have been reviewed or authored by nsp16 binds nsp10 (9683429)