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Query author contributions in Reactome

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Details on Person FLT3 Y597_K602dup [plasma membrane]

Class:IdEntityWithAccessionedSequence:9683381
_displayNameFLT3 Y597_K602dup [plasma membrane]
_timestamp2023-04-01 03:59:36
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9683382] Rothfels, Karen, 2020-04-14
crossReference[DatabaseIdentifier:9832464] COSMIC:COSV54064232
disease[Disease:1500689] cancer
[Disease:9630839] acute myeloid leukemia
endCoordinate993
hasModifiedResidue[FragmentInsertionModification:9683377] Insertion of residues 597 to 602 at 603 from UniProt:P36888 FLT3
literatureReference[LiteratureReference:9683350] Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product
[LiteratureReference:9697825] Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells
modified[InstanceEdit:9690073] Rothfels, Karen, 2020-05-25
[InstanceEdit:9697942] Rothfels, Karen, 2020-08-21
[InstanceEdit:9832462] Orlic-Milacic, Marija, 2023-04-01
[InstanceEdit:9832466] Orlic-Milacic, Marija, 2023-04-01
nameFLT3 Y597_K602dup
STK-1
Mt1
Pt. VI
referenceEntity[ReferenceGeneProduct:54914] UniProt:P36888 FLT3 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9683383] R-HSA-9683381.2
startCoordinate27
(hasComponent)[Complex:9691985] FLT3 K602_W603insYEYDLK dimer [plasma membrane] [Homo sapiens]
(hasMember)[CandidateSet:9691152] juxtamembrane domain mutants of FLT3 [plasma membrane] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9905261] Update Tracker - [EntityWithAccessionedSequence:9683381] FLT3 Y597_K602dup [plasma membrane] - v85:[modifyName]
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No pathways have been reviewed or authored by FLT3 Y597_K602dup [plasma membrane] (9683381)
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