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Details on Person Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein
| Class:Id | LiteratureReference:9683094 |
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| _displayName | Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein |
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| _timestamp | 2020-04-14 04:06:05 |
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| author | [Person:9682963] Ritchie, Gayle
[Person:9682869] Harvey, David J
[Person:9682958] Feldmann, Friederike
[Person:9683092] Stroeher, Ute
[Person:9678365] Feldmann, Heinz
[Person:9683045] Royle, Louise
[Person:8848852] Dwek, Raymond A
[Person:8848843] Rudd, Pauline M |
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| created | [InstanceEdit:9683039] Stephan, Ralf, 2020-04-14 |
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| journal | Virology |
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| pages | 257-69 |
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| pubMedIdentifier | 20129637 |
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| title | Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein |
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| volume | 399 |
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| year | 2010 |
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| (literatureReference) | [BlackBoxEvent:9683648] Spike trimer glycoside chains are extended [Homo sapiens]
[BlackBoxEvent:9683669] E protein gets N-glycosylated [Homo sapiens]
[BlackBoxEvent:9683755] Spike protein gets N-glycosylated [Homo sapiens]
[BlackBoxEvent:9694790] E protein gets N-glycosylated [Homo sapiens]
[Summation:9682862] Glycosyltransferases in the endoplasmatic reticulum are resp...
[Summation:9683002] In the cis- to medial Golgis, conversion of high-mannose to ...
[Summation:9694765] This COVID-19 BlackBoxEvent instance was generated via electronic inference from a curated CoV-1 (Human SARS coronavirus) Reactome instance. In Reactome, inference is the process used to automatically create orthologous Pathways, Reactions and PhysicalEntities from our expertly curated data (https://reactome.org/documentation/inferred-events).
In the cis- to medial Golgis, conversion of high-mannose to complex type N-glycans side chains of Spike occurs. The N-acetylglucosaminyltransferase called GlcNAc-TI (MGAT1) adds a GlcNAc residue in the core of some high-mannose chains (Ritchie et al, 2010; Nal et al, 2005, Song et al, 2004).
[EntityWithAccessionedSequence:9683594] N-glycan Spike [endoplasmic reticulum lumen] [Human SARS coronavirus]
[EntityWithAccessionedSequence:9683608] trimmed N-glycan Spike [endoplasmic reticulum lumen] [Human SARS coronavirus]
[EntityWithAccessionedSequence:9683617] complex N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] [Human SARS coronavirus] |
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