Reactome: A Curated Pathway Database
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Query author contributions in Reactome

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Details on Person May, Bruce, 2020-04-14

Class:IdInstanceEdit:9682769
_displayNameMay, Bruce, 2020-04-14
_timestamp2020-04-14 03:45:02
author[Person:203835] May, Bruce
dateTime2020-04-14 03:44:36
(modified)[Summation:389129] Following dimerization of the CSF-1 receptor (CSF1R), it und...
[Summation:389138] Colony-stimulating factor 1 receptor (CSF1R, CSF-1R) is a pr...
[BlackBoxEvent:9680348] PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated [Homo sapiens]
[Pathway:9680350] Signaling by CSF1 (M-CSF) in myeloid cells [Homo sapiens]
[Complex:9680374] CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:p-Y-CBL:GRB2:SOS1:p-Y-GAB2:p-Y-GAB3:GRAP2:INPP5D:INPPL1:PI3K:PTPN11:p-Y-SHC1:p-Y-PLCG2 [plasma membrane] [Homo sapiens]
[Reaction:9680389] CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 [Homo sapiens]
[BlackBoxEvent:9680646] Pik3r11:Pik3ca,b,d (Pi3k), Plcg2 (PLCgamma2), Grb2:Sos1, Shc1 (Shc), Ptpn11 (Shp2), Grb2:Gab2, Grb2:Gab3, Grap2 (MONA), Cbl:Grb2, Inpp5d (SHIP1), Inppl1 (SHIP2) bind p-8Y-Csf1r and are activated [Mus musculus]
[Complex:9680664] Csf1 dimer:PolyUb,p-8Y-Csf1r dimer:Fyn,Hck,Src,Yes1:p-Y-Gab2:p-Y-Gab3:Grap2:Inpp5d:Inppl1:Pi3k:Ptpn11:p-Y-Shc1:p-Y-Plcg2 [plasma membrane] [Mus musculus]
[Reaction:9680706] Csf1r trans-autophosphorylates on multiple tyrosine residues [Mus musculus]
[Summation:9680716] The Pik3r1 (p85alpha) subunit of phosphatidylinositol 3-kina...
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No pathways have been reviewed or authored by May, Bruce, 2020-04-14 (9682769)