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Details on Person p-6Y-FLT3 I836delinsLD [plasma membrane]

Class:Id	EntityWithAccessionedSequence:9682380
_displayName	p-6Y-FLT3 I836delinsLD [plasma membrane]
_timestamp	2023-04-01 03:50:16
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9682381] Rothfels, Karen, 2020-04-08
disease	[Disease:1500689] cancer [Disease:9630839] acute myeloid leukemia
endCoordinate	993
hasModifiedResidue	[FragmentReplacedModification:9682361] Replacement of residues 836 to 836 by LD [ModifiedResidue:9604760] O4'-phospho-L-tyrosine at 589 [ModifiedResidue:9604750] O4'-phospho-L-tyrosine at 591 [ModifiedResidue:9604772] O4'-phospho-L-tyrosine at 599 [ModifiedResidue:9604762] O4'-phospho-L-tyrosine at 768 [ModifiedResidue:9604765] O4'-phospho-L-tyrosine at 955 [ModifiedResidue:9604743] O4'-phospho-L-tyrosine at 969
literatureReference	[LiteratureReference:9682272] Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
modified	[InstanceEdit:9832461] Orlic-Milacic, Marija, 2023-04-01
name	p-6Y-FLT3 I836delinsLD STK-1
referenceEntity	[ReferenceGeneProduct:54914] UniProt:P36888 FLT3 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9682416] R-HSA-9682380.2
startCoordinate	27
(hasComponent)	[Complex:9682388] p-6Y FLT3 I836LInsD dimer [plasma membrane] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9905627] Update Tracker - [EntityWithAccessionedSequence:9682380] p-6Y-FLT3 I836delinsLD [plasma membrane] - v85:[modifyName]
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No pathways have been reviewed or authored by p-6Y-FLT3 I836delinsLD [plasma membrane] (9682380)