Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person In response to Csf1, Plcg2 (phospholipase C gamma2) associat...

Class:IdSummation:9682185
_displayNameIn response to Csf1, Plcg2 (phospholipase C gamma2) associat...
_timestamp2020-04-14 03:47:02
created[InstanceEdit:9682186] May, Bruce, 2020-04-08
modified[InstanceEdit:9682769] May, Bruce, 2020-04-14
textIn response to Csf1, Plcg2 (phospholipase C gamma2) associates with Csf1r, is activated by phosphorylation, and hydrolyzes phosphatidylcholine to yield choline phosphate (ChoP, phosphocholine) and 1,2-diacylglycerol (Xu et al. 1993, Bourgin-Hierle et al. 2008). Plcg2 activates pathways that enhance differentiation of macrophages (Bourette et al. 1997).
(summation)[Reaction:9682158] Csf1r-associated Plcg2 hydrolyzes phosphatidylcholine yielding choline phosphate and 1,2-diacylglycerol [Mus musculus]
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