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Details on Person IL1R1 binds IL1R1 inhibitors

Class:IdReaction:9681763
_displayNameIL1R1 binds IL1R1 inhibitors
_doReleaseTRUE
_timestamp2020-06-02 10:05:30
authored[InstanceEdit:9681760] Jassal, Bijay, 2020-04-06
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:9681760] Jassal, Bijay, 2020-04-06
definitionInhibition
edited[InstanceEdit:9681760] Jassal, Bijay, 2020-04-06
input[DefinedSet:9681804] IL1R1 inhibitors [extracellular region]
[EntityWithAccessionedSequence:197595] IL1R1 [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9681796] Physiologic role of interleukin-1 receptor antagonist
[LiteratureReference:9681768] Multicenter Study of a Novel Topical Interleukin-1 Receptor Inhibitor, Isunakinra, in Subjects With Moderate to Severe Dry Eye Disease
[LiteratureReference:9690515] Natural and recombinant human IL-1 receptor antagonists block the effects of IL-1 on bone resorption and prostaglandin production
modified[InstanceEdit:9683526] Jassal, Bijay, 2020-04-17
[InstanceEdit:9684051] Jassal, Bijay, 2020-04-20
[InstanceEdit:9687446] D'Eustachio, Peter, 2020-05-08
[InstanceEdit:9688550] Jassal, Bijay, 2020-05-14
[InstanceEdit:9688754] Jassal, Bijay, 2020-05-14
[InstanceEdit:9690511] Jassal, Bijay, 2020-06-02
[InstanceEdit:9690514] Jassal, Bijay, 2020-06-02
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameIL1R1 binds IL1R1 inhibitors
output[Complex:9681780] IL1R1:IL1R1 inhibitors [plasma membrane] [Homo sapiens]
releaseDate2020-06-10
reviewed[InstanceEdit:9688552] Shoichet, Brian, 2020-05-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9681811] R-HSA-9681763.3
summation[Summation:9681752] The IL1 family includes two agonists, IL1α and IL1β, and a n...
(hasEvent)[Pathway:9020702] Interleukin-1 signaling [Homo sapiens]
[Pathway:9679191] Potential therapeutics for SARS [Homo sapiens]
(updatedInstance)[_UpdateTracker:9776787] Update Tracker - [Reaction:9681763] IL1R1 binds IL1R1 inhibitors - v74:[addLiteratureReference, add_removeInput, modifyText]
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No pathways have been reviewed or authored by IL1R1 binds IL1R1 inhibitors (9681763)