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Details on Person Both src-dependent and -independent mechanisms mediate phosphatidylinositol 3-kinase regulation of colony-stimulating factor 1-activated mitogen-activated protein kinases in myeloid progenitors

Class:IdLiteratureReference:9681709
_displayNameBoth src-dependent and -independent mechanisms mediate phosphatidylinositol 3-kinase regulation of colony-stimulating factor 1-activated mitogen-activated protein kinases in myeloid progenitors
_timestamp2020-04-04 07:11:11
author[Person:9681713] Lee, A W
[Person:9681708] States, D J
created[InstanceEdit:9681720] May, Bruce, 2020-04-04
journalMol. Cell. Biol.
pages6779-98
pubMedIdentifier10958675
titleBoth src-dependent and -independent mechanisms mediate phosphatidylinositol 3-kinase regulation of colony-stimulating factor 1-activated mitogen-activated protein kinases in myeloid progenitors
volume20
year2000
(literatureReference)[Summation:9682576] SOS1 (SOS) is stably bound to GRB2, which transiently associ...
[BlackBoxEvent:9680646] Pik3r11:Pik3ca,b,d (Pi3k), Plcg2 (PLCgamma2), Grb2:Sos1, Shc1 (Shc), Ptpn11 (Shp2), Grb2:Gab2, Grb2:Gab3, Grap2 (MONA), Cbl:Grb2, Inpp5d (SHIP1), Inppl1 (SHIP2) bind p-8Y-Csf1r and are activated [Mus musculus]
[Reaction:9682182] Csf1r-associated PI3K phosphorylates phosphatidylinositol 4,5-bisphosphate [Mus musculus]
[Reaction:9682572] Csf1r-associated Sos1 mediates exchange of GTP for GDP bound to Ras [Mus musculus]
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