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Details on Person Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs)

Class:IdLiteratureReference:9680303
_displayNameMechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs)
_timestamp2020-03-26 19:02:02
author[Person:5686660] Duensing, Anette
[Person:9680302] Medeiros, Fabiola
[Person:9680301] McConarty, Bryna
[Person:9680305] Joseph, Nora E
[Person:9680304] Panigrahy, Dipak
[Person:9671433] Singer, Samuel
[Person:9671895] Fletcher, Christopher D M
[Person:9669081] Demetri, George D
[Person:9669087] Fletcher, Jonathan A
created[InstanceEdit:9680300] Rothfels, Karen, 2020-03-26
journalOncogene
pages3999-4006
pubMedIdentifier15007386
titleMechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs)
volume23
year2004
(literatureReference)[BlackBoxEvent:9670412] Phosphorylation of STATs downstream of KIT mutants [Homo sapiens]
[Reaction:9670416] Recruitment of STATs by KIT mutants [Homo sapiens]
[Reaction:9670417] Dimerization of STATs downstream of KIT mutants [Homo sapiens]
[Reaction:9670426] Disassociation and translocation of STATs to the nucleus downstream of KIT mutants [Homo sapiens]
[Reaction:9670433] KIT mutants:PI3K catalyze synthesis of PIP3 [Homo sapiens]
[Pathway:9670439] Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants [Homo sapiens]
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No pathways have been reviewed or authored by Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs) (9680303)