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Details on Person WDR5 and MYC positively regulate transcription of genes needed for biomass increase

Class:Id	BlackBoxEvent:9680228
_displayName	WDR5 and MYC positively regulate transcription of genes needed for biomass increase
_doRelease	FALSE
_timestamp	2020-03-26 01:52:35
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:9680229] Orlic-Milacic, Marija, 2020-03-26
input	[CandidateSet:9679915] WDR5 and MYC metabolic target genes [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9679901] Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance
modified	[InstanceEdit:9680237] Orlic-Milacic, Marija, 2020-03-26
name	WDR5 and MYC positively regulate transcription of genes needed for biomass increase
output	[CandidateSet:9680234] Transcripts of WDR5 and MYC metabolic target genes [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9680218] WDR5 recruits MYC to promoters of metabolic genes [Homo sapiens] [Reaction:9679913] WDR5 binds promoters of metabolic genes [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9680230] Positive gene expression regulation by 'WDR5:MYC:metabolic target genes [nucleoplasm]'
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9680231] R-HSA-9680228.1
summation	[Summation:9680235] The complex of WDR5 and MYC directly stimulates transcriptio...
(hasEvent)	[Pathway:9680220] WDR5 and MYC regulate transcription of metabolic genes [Homo sapiens]
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