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Details on Person p7Y-KIT S476I [plasma membrane]

Class:Id	EntityWithAccessionedSequence:9680156
_displayName	p7Y-KIT S476I [plasma membrane]
_timestamp	2020-03-25 20:52:55
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9680162] Rothfels, Karen, 2020-03-25
crossReference	[DatabaseIdentifier:9680002] COSMIC:COSV55419524 [DatabaseIdentifier:9680010] COSMIC:COSM29344
disease	[Disease:1500689] cancer [Disease:9669013] mast cell neoplasm [Disease:9648487] lung small cell carcinoma [Disease:9661830] gastrointestinal stromal tumor
endCoordinate	976
hasModifiedResidue	[ReplacedResidue:9680092] L-serine 476 replaced with L-isoleucine [ModifiedResidue:205176] O4'-phospho-L-tyrosine at 568 [ModifiedResidue:205169] O4'-phospho-L-tyrosine at 570 [ModifiedResidue:205278] O4'-phospho-L-tyrosine at 703 [ModifiedResidue:205171] O4'-phospho-L-tyrosine at 721 [ModifiedResidue:205288] O4'-phospho-L-tyrosine at 730 [ModifiedResidue:205235] O4'-phospho-L-tyrosine at 823 [ModifiedResidue:205246] O4'-phospho-L-tyrosine at 936
literatureReference	[LiteratureReference:9679981] Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations
name	p7Y-KIT S476I
referenceEntity	[ReferenceGeneProduct:58103] UniProt:P10721 KIT [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9680174] R-HSA-9680156.1
startCoordinate	26
(hasComponent)	[Complex:9680164] p7Y-KIT S476I dimer [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by p7Y-KIT S476I [plasma membrane] (9680156)