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Details on Person KIT A502_Y503dup [plasma membrane]

Class:Id	EntityWithAccessionedSequence:9680030
_displayName	KIT A502_Y503dup [plasma membrane]
_timestamp	2020-03-25 20:48:56
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9680031] Rothfels, Karen, 2020-03-25
crossReference	[DatabaseIdentifier:9679994] COSMIC:COSM12444
disease	[Disease:1500689] cancer [Disease:9661830] gastrointestinal stromal tumor
endCoordinate	976
hasModifiedResidue	[FragmentInsertionModification:9680027] Insertion of residues 502 to 503 at 504 from UniProt:P10721 KIT
literatureReference	[LiteratureReference:9679981] Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations
name	KIT A502_Y503dup
referenceEntity	[ReferenceGeneProduct:58103] UniProt:P10721 KIT [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9680032] R-HSA-9680030.1
startCoordinate	26
(hasComponent)	[Complex:9680034] KIT A502_Y503dup dimer [plasma membrane] [Homo sapiens]
(hasMember)	[CandidateSet:9680195] extracellular domain mutants of KIT [plasma membrane] [Homo sapiens] [CandidateSet:9681384] ripretinib-sensitive KIT mutants [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by KIT A502_Y503dup [plasma membrane] (9680030)