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Details on Person RIPK1 binds ponatinib

Class:IdReaction:9679839
_displayNameRIPK1 binds ponatinib
_doReleaseTRUE
_timestamp2021-01-21 14:55:23
authored[InstanceEdit:9679866] Jassal, Bijay, 2020-03-25
compartment[Compartment:876] plasma membrane
[Compartment:984] extracellular region
[Compartment:7660] nucleoplasm
created[InstanceEdit:9679866] Jassal, Bijay, 2020-03-25
definitionInhibition
edited[InstanceEdit:9679866] Jassal, Bijay, 2020-03-25
input[EntityWithAccessionedSequence:937073] RIPK1 [plasma membrane] [Homo sapiens]
[ChemicalDrug:9679746] ponatinib [extracellular region]
literatureReference[LiteratureReference:9679817] Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1
[LiteratureReference:9685668] Targeting RIPK1 for the treatment of human diseases
modified[InstanceEdit:9679897] Jassal, Bijay, 2020-03-25
[InstanceEdit:9685409] Jassal, Bijay, 2020-04-23
[InstanceEdit:9685670] Jassal, Bijay, 2020-04-24
[InstanceEdit:9687446] D'Eustachio, Peter, 2020-05-08
[InstanceEdit:9687978] Jassal, Bijay, 2020-05-13
[InstanceEdit:9688550] Jassal, Bijay, 2020-05-14
[InstanceEdit:9688754] Jassal, Bijay, 2020-05-14
[InstanceEdit:9713163] Jassal, Bijay, 2021-01-21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRIPK1 binds ponatinib
output[Complex:9679749] RIPK1:ponatinib [plasma membrane] [Homo sapiens]
releaseDate2020-06-10
reviewed[InstanceEdit:9688552] Shoichet, Brian, 2020-05-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9679887] R-HSA-9679839.3
summation[Summation:9685671] TNF-alpha signaling leads to the assembly of a large recepto...
(hasEvent)[Pathway:9679191] Potential therapeutics for SARS [Homo sapiens]
(updatedInstance)[_UpdateTracker:9776439] Update Tracker - [Reaction:9679839] RIPK1 binds ponatinib - v76:[add_removeInput]
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No pathways have been reviewed or authored by RIPK1 binds ponatinib (9679839)