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Details on Person SIGMAR1 binds fluvoxamine

Class:IdReaction:9679780
_displayNameSIGMAR1 binds fluvoxamine
_doReleaseTRUE
_timestamp2022-05-19 07:34:18
authored[InstanceEdit:9679866] Jassal, Bijay, 2020-03-25
compartment[Compartment:70101] cytosol
[Compartment:984] extracellular region
created[InstanceEdit:9679866] Jassal, Bijay, 2020-03-25
definitionAntagonist
edited[InstanceEdit:9679866] Jassal, Bijay, 2020-03-25
input[EntityWithAccessionedSequence:9679757] SIGMAR1 [cytosol] [Homo sapiens]
[ChemicalDrug:9679783] fluvoxamine [cytosol]
literatureReference[LiteratureReference:9679739] From α4β2 Nicotinic Ligands to the Discovery of σ1 Receptor Ligands: Pharmacophore Analysis and Rational Design
[LiteratureReference:9685760] High occupancy of sigma-1 receptors in the human brain after single oral administration of fluvoxamine: a positron emission tomography study using [11C]SA4503
[LiteratureReference:9685785] Chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release
[URL:9774144] https://www.accessdata.fda.gov/drugsatfda_docs/nda/2020/EUA%20110%20Fluvoxamine%20Decisional%20Memo_Redacted.pdf
modified[InstanceEdit:9679897] Jassal, Bijay, 2020-03-25
[InstanceEdit:9685409] Jassal, Bijay, 2020-04-23
[InstanceEdit:9685756] Jassal, Bijay, 2020-04-27
[InstanceEdit:9687446] D'Eustachio, Peter, 2020-05-08
[InstanceEdit:9688550] Jassal, Bijay, 2020-05-14
[InstanceEdit:9688754] Jassal, Bijay, 2020-05-14
[InstanceEdit:9774143] Stephan, Ralf, 2022-05-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSIGMAR1 binds fluvoxamine
output[Complex:9679768] SIGMAR1:fluvoxamine [cytosol] [Homo sapiens]
releaseDate2020-06-10
reviewed[InstanceEdit:9688552] Shoichet, Brian, 2020-05-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9679882] R-HSA-9679780.3
summation[Summation:9685817] Among selective serotonin reuptake inhibitors (SSRIs), fluvo...
(hasEvent)[Pathway:9679191] Potential therapeutics for SARS [Homo sapiens]
(updatedInstance)[_UpdateTracker:9846978] Update Tracker - [Reaction:9679780] SIGMAR1 binds fluvoxamine - v82:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by SIGMAR1 binds fluvoxamine (9679780)